Ostarine Powder (MK-2866) | 2 Grams

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Ostarine (MK-2866) Powder — 2 Grams

Ostarine, also designated MK-2866, GTx-024, or enobosarm,
is among the most extensively studied selective androgen receptor modulators (SARMs) in the published literature.
This listing is a research-grade reference compound supplied in powder form for
in vitro and laboratory investigation. Every batch is third-party verified for identity and purity
and accompanied by a downloadable Certificate of Analysis.

• Min. 98% purity (HPLC)
• Third-party verified
• 2,000 mg net
• Batch-specific COA
• UV-resistant foil pouch

Research Context

Ostarine emerged in the late 1990s and early 2000s as a non-steroidal SARM investigated in preclinical and
clinical settings for conditions involving muscle wasting and bone loss.^[1][2] As a selective
androgen receptor modulator, it binds the androgen receptor with tissue-selective activity, a property that has
made it a frequent subject in studies of muscle and skeletal physiology.^[1][5] Published work includes
a placebo-controlled Phase II trial in older adults^[1] and ovariectomized-rat models examining
bone healing and post-menopausal osteoporosis endpoints.^[2][3] It has also appeared in oncology
research contexts as enobosarm.^[4]

This material is supplied strictly as a reference compound to support such laboratory investigation. It is
not a therapeutic product, dietary supplement, or sports supplement, and no clinical or
performance outcomes are claimed or implied for any individual.

Scientific References

1. Dalton JT, Barnette KG, Bohl CE, et al. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial. J Cachexia Sarcopenia Muscle. 2011;2(3):153–161.
2. Komrakova M, Furtwängler J, Hoffmann DB, et al. The Selective Androgen Receptor Modulator Ostarine Improves Bone Healing in Ovariectomized Rats. Calcif Tissue Int. 2020;106(2):147–157.
3. Hoffmann DB, Komrakova M, Pflug S, et al. Evaluation of ostarine as a selective androgen receptor modulator in a rat model of postmenopausal osteoporosis. J Bone Miner Metab. 2019;37(2):243–255.
4. Yuan Y, Lee JS, Yost SE, et al. A Phase II Clinical Trial of Pembrolizumab and Enobosarm in Patients with Androgen Receptor-Positive Metastatic Triple-Negative Breast Cancer. Oncologist. 2021;26(2):99–e217.
5. Van Wagoner RM, Eichner A, Bhasin S, Deuster PA, Eichner D. Chemical Composition and Labeling of Substances Marketed as Selective Androgen Receptor Modulators and Sold via the Internet. JAMA. 2017;318(20):2004–2010.
6. ClinicalTrials.gov. Enobosarm (GTx-024) study record NCT02368691.